Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice
Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice
About this item
Full title
Author / Creator
Publisher
England: Nature Publishing Group
Journal title
Language
English
Formats
Publication information
Publisher
England: Nature Publishing Group
Subjects
More information
Scope and Contents
Contents
Alzheimer's disease (AD) is a progressive neurodegenerative disease with cognitive dysfunction as its major clinical symptom. However, there is no disease-modifying small molecular medicine to effectively slow down progression of the disease. Here, we show an optimized asparagine endopeptidase (AEP, also known as δ-secretase) inhibitor, #11 A, that...
Alternative Titles
Full title
Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10789813
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10789813
Other Identifiers
ISSN
0893-133X
E-ISSN
1740-634X
DOI
10.1038/s41386-023-01774-2
