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Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10791586

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

About this item

Full title

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2024-01, Vol.42 (1), p.72-86

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been difficult in part because a simple method to simultaneously quantify their abundance and chemical modifications is lacking. Here we introduce Nano-tRNAseq, a nanopore-based approach to sequence native tRNA populations that provides quantitative estimates of bot...

Alternative Titles

Full title

Quantitative analysis of tRNA abundance and modifications by nanopore RNA sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10791586

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10791586

Other Identifiers

ISSN

1087-0156,1546-1696

E-ISSN

1546-1696

DOI

10.1038/s41587-023-01743-6

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