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Therapy-induced APOBEC3A drives evolution of persistent cancer cells

Therapy-induced APOBEC3A drives evolution of persistent cancer cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10804446

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Acquired drug resistance to anticancer targeted therapies remains an unsolved clinical problem. Although many drivers of acquired drug resistance have been identified
1

4
, the underlying molecular mechanisms shaping tumour evolution during treatment are incompletely understood. Genomic profiling of patient tumours has implicated apol...

Alternative Titles

Full title

Therapy-induced APOBEC3A drives evolution of persistent cancer cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10804446

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10804446

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06303-1

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