Therapy-induced APOBEC3A drives evolution of persistent cancer cells
Therapy-induced APOBEC3A drives evolution of persistent cancer cells
About this item
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Author / Creator
Isozaki, Hideko , Sakhtemani, Ramin , Abbasi, Ammal , Nikpour, Naveed , Stanzione, Marcello , Oh, Sunwoo , Langenbucher, Adam , Monroe, Susanna , Su, Wenjia , Cabanos, Heidie Frisco , Siddiqui, Faria M. , Phan, Nicole , Jalili, Pégah , Timonina, Daria , Bilton, Samantha , Gomez-Caraballo, Maria , Archibald, Hannah L. , Nangia, Varuna , Dionne, Kristin , Riley, Amanda , Lawlor, Matthew , Banwait, Mandeep Kaur , Cobb, Rosemary G. , Zou, Lee , Dyson, Nicholas J. , Ott, Christopher J. , Benes, Cyril , Getz, Gad , Chan, Chang S. , Shaw, Alice T. , Gainor, Justin F. , Lin, Jessica J. , Sequist, Lecia V. , Piotrowska, Zofia , Yeap, Beow Y. , Engelman, Jeffrey A. , Lee, Jake June-Koo , Maruvka, Yosef E. , Buisson, Rémi , Lawrence, Michael S. and Hata, Aaron N.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Acquired drug resistance to anticancer targeted therapies remains an unsolved clinical problem. Although many drivers of acquired drug resistance have been identified
1
–
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, the underlying molecular mechanisms shaping tumour evolution during treatment are incompletely understood. Genomic profiling of patient tumours has implicated apol...
Alternative Titles
Full title
Therapy-induced APOBEC3A drives evolution of persistent cancer cells
Authors, Artists and Contributors
Author / Creator
Sakhtemani, Ramin
Abbasi, Ammal
Nikpour, Naveed
Stanzione, Marcello
Oh, Sunwoo
Langenbucher, Adam
Monroe, Susanna
Su, Wenjia
Cabanos, Heidie Frisco
Siddiqui, Faria M.
Phan, Nicole
Jalili, Pégah
Timonina, Daria
Bilton, Samantha
Gomez-Caraballo, Maria
Archibald, Hannah L.
Nangia, Varuna
Dionne, Kristin
Riley, Amanda
Lawlor, Matthew
Banwait, Mandeep Kaur
Cobb, Rosemary G.
Zou, Lee
Dyson, Nicholas J.
Ott, Christopher J.
Benes, Cyril
Getz, Gad
Chan, Chang S.
Shaw, Alice T.
Gainor, Justin F.
Lin, Jessica J.
Sequist, Lecia V.
Piotrowska, Zofia
Yeap, Beow Y.
Engelman, Jeffrey A.
Lee, Jake June-Koo
Maruvka, Yosef E.
Buisson, Rémi
Lawrence, Michael S.
Hata, Aaron N.
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10804446
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10804446
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06303-1