Systems engineering of Escherichia coli for high-level glutarate production from glucose
Systems engineering of Escherichia coli for high-level glutarate production from glucose
About this item
Full title
Author / Creator
Zhang, Zhilan , Chu, Ruyin , Wei, Wanqing , Song, Wei , Ye, Chao , Chen, Xiulai , Wu, Jing , Liu, Liming and Gao, Cong
Publisher
England: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
England: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Glutarate is a key monomer in polyester and polyamide production. The low efficiency of the current biosynthetic pathways hampers its production by microbial cell factories. Herein, through metabolic simulation, a lysine-overproducing E. coli strain Lys5 is engineered, achieving titer, yield, and productivity of 195.9 g/L, 0.67 g/g glucose, and 5.4...
Alternative Titles
Full title
Systems engineering of Escherichia coli for high-level glutarate production from glucose
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10838341
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10838341
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-45448-z
