Blebs promote cell survival by assembling oncogenic signalling hubs
Blebs promote cell survival by assembling oncogenic signalling hubs
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Most human cells require anchorage for survival. Cell–substrate adhesion activates diverse signalling pathways, without which cells undergo anoikis—a form of programmed cell death
1
. Acquisition of anoikis resistance is a pivotal step in cancer disease progression, as metastasizing cells often lose firm attachment to surrounding tissue
2<...
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Full title
Blebs promote cell survival by assembling oncogenic signalling hubs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881276
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881276
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-023-05758-6