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Blebs promote cell survival by assembling oncogenic signalling hubs

Blebs promote cell survival by assembling oncogenic signalling hubs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881276

Blebs promote cell survival by assembling oncogenic signalling hubs

About this item

Full title

Blebs promote cell survival by assembling oncogenic signalling hubs

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-03, Vol.615 (7952), p.517-525

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Most human cells require anchorage for survival. Cell–substrate adhesion activates diverse signalling pathways, without which cells undergo anoikis—a form of programmed cell death
1
. Acquisition of anoikis resistance is a pivotal step in cancer disease progression, as metastasizing cells often lose firm attachment to surrounding tissue
2<...

Alternative Titles

Full title

Blebs promote cell survival by assembling oncogenic signalling hubs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881276

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881276

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-023-05758-6

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