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Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10895701

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

About this item

Full title

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2023-07, Vol.30 (7), p.1001-1011

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

A wide range of endogenous and xenobiotic organic ions require facilitated transport systems to cross the plasma membrane for their disposition. In mammals, organic cation transporter (OCT) subtypes 1 and 2 (OCT1 and OCT2, also known as SLC22A1 and SLC22A2, respectively) are polyspecific transporters responsible for the uptake and clearance of stru...

Alternative Titles

Full title

Molecular basis of polyspecific drug and xenobiotic recognition by OCT1 and OCT2

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10895701

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10895701

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/s41594-023-01017-4

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