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The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into mac...

The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into mac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10916879

The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes

About this item

Full title

The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes

Publisher

United States: American Society for Cell Biology

Journal title

Molecular biology of the cell, 2024-03, Vol.35 (3), p.ar38-ar38

Language

English

Formats

Publication information

Publisher

United States: American Society for Cell Biology

More information

Scope and Contents

Contents

The ubiquitination of transmembrane receptors regulates endocytosis, intracellular traffic, and signal transduction. Bone marrow-derived macrophages from myeloid Cbl
and Cbl-b
double knockout (DKO) mice display sustained proliferation mirroring the myeloproliferative disease that these mice succumb to. Here, we found that the ubiquitin ligase...

Alternative Titles

Full title

The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10916879

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10916879

Other Identifiers

ISSN

1059-1524

E-ISSN

1939-4586

DOI

10.1091/mbc.E23-09-0345

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