The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into mac...
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes
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United States: American Society for Cell Biology
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Language
English
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Publisher
United States: American Society for Cell Biology
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Contents
The ubiquitination of transmembrane receptors regulates endocytosis, intracellular traffic, and signal transduction. Bone marrow-derived macrophages from myeloid Cbl
and Cbl-b
double knockout (DKO) mice display sustained proliferation mirroring the myeloproliferative disease that these mice succumb to. Here, we found that the ubiquitin ligase...
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Full title
The ubiquitin ligases Cbl and Cbl-b regulate macrophage growth by controlling CSF-1R import into macropinosomes
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10916879
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10916879
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ISSN
1059-1524
E-ISSN
1939-4586
DOI
10.1091/mbc.E23-09-0345