Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Dysfunctional autophagy has been implicated in the pathogenesis of Alzheimer’s disease (AD). Previous evidence suggested disruptions of multiple stages of the autophagy-lysosomal pathway in affected neurons. However, whether and how deregulated autophagy in microglia, a cell type with an important link to AD, contributes to AD progression remains e...
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Full title
Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10950302
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10950302
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/s41556-023-01158-0
