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Tau-targeting therapies for Alzheimer disease: current status and future directions

Tau-targeting therapies for Alzheimer disease: current status and future directions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10965012

Tau-targeting therapies for Alzheimer disease: current status and future directions

About this item

Full title

Tau-targeting therapies for Alzheimer disease: current status and future directions

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Neurology, 2023-12, Vol.19 (12), p.715-736

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Alzheimer disease (AD) is the most common cause of dementia in older individuals. AD is characterized pathologically by amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the brain, with associated loss of synapses and neurons, which eventually results in dementia. Many of the early attempts to develop treatments for AD focused on Aβ, but a...

Alternative Titles

Full title

Tau-targeting therapies for Alzheimer disease: current status and future directions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10965012

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10965012

Other Identifiers

ISSN

1759-4758,1759-4766

E-ISSN

1759-4766

DOI

10.1038/s41582-023-00883-2

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