Y chromosome loss in cancer drives growth by evasion of adaptive immunity
Y chromosome loss in cancer drives growth by evasion of adaptive immunity
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Loss of the Y chromosome (LOY) is observed in multiple cancer types, including 10–40% of bladder cancers
1
–
6
, but its clinical and biological significance is unknown. Here, using genomic and transcriptomic studies, we report that LOY correlates with poor prognoses in patients with bladder cancer. We performed in-depth studies of natu...
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Full title
Y chromosome loss in cancer drives growth by evasion of adaptive immunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10975863
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10975863
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06234-x
