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PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients

PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11029035

PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients

About this item

Full title

PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2014-04, Vol.63 (4), p.395-406

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The programmed death-1 (PD-1) molecule is mainly expressed on functionally “exhausted” CD8
+
T cells, dampening the host antitumor immune response. We evaluated the ratio between effective and regulatory T cells (Tregs) and PD-1 expression as a prognostic factor for operable breast cancer patients. A series of 218 newly diagnosed invasive bre...

Alternative Titles

Full title

PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11029035

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11029035

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-014-1519-x

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