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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during p...

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072213

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

About this item

Full title

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2021-01, Vol.78 (1), p.287-298

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Unveiling the key pathways underlying postnatal beta-cell proliferation can be instrumental to decipher the mechanisms of beta-cell mass plasticity to increased physiological demand of insulin during weight gain and pregnancy. Using transcriptome and global Serine Threonine Kinase activity (STK) analyses of islets from newborn (10 days old) and adu...

Alternative Titles

Full title

The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072213

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-020-03499-7

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