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ArticlesPeer ReviewedFull Text
Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes
Author / Creator:Pasquier, Adrien ; Vivot, Kevin ; Erbs, Eric ; Spiegelhalter, Coralie ; Zhang, Zhirong ; Aubert, Victor ; Liu, Zengzhen ; Senkara, Meryem ; Maillard, Elisa ; Pinget, Michel ; Kerr-Conte, Julie ; Pattou, François ; Marciniak, Gilbert ; Ganzhorn, Axel ; Ronchi, Paolo ; Schieber, Nicole L. ; Schwab, Yannick ; Saftig, Paul ; Goginashvili, Alexander ; Ricci, Romeo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3312-14, Article 3312
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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity
Author / Creator:Bricambert, Julien ; Alves-Guerra, Marie-Clotilde ; Esteves, Pauline ; Prip-Buus, Carina ; Bertrand-Michel, Justine ; Guillou, Hervé ; Chang, Christopher J. ; Vander Wal, Mark N. ; Canonne-Hergaux, François ; Mathurin, Philippe ; Raverdy, Violeta ; Pattou, François ; Girard, Jean ; Postic, Catherine ; Dentin, Renaud
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.2092-18, Article 2092
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Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
Author / Creator:Plaisance, Valérie ; Brajkovic, Saška ; Tenenbaum, Mathie ; Favre, Dimitri ; Ezanno, Hélène ; Bonnefond, Amélie ; Bonner, Caroline ; Gmyr, Valéry ; Kerr-Conte, Julie ; Gauthier, Benoit R. ; Widmann, Christian ; Waeber, Gérard ; Pattou, François ; Froguel, Philippe ; Abderrahmani, Amar
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-09, Vol.11 (9), p.e0163046-e0163046
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The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward
Author / Creator:Ndiaye, Fatou K. ; Huyvaert, Marlène ; Ortalli, Ana ; Canouil, Mickaël ; Lecoeur, Cécile ; Verbanck, Marie ; Lobbens, Stéphane ; Khamis, Amna ; Marselli, Lorella ; Marchetti, Piero ; Kerr-Conte, Julie ; Pattou, François ; Marre, Michel ; Roussel, Ronan ; Balkau, Beverley ; Froguel, Philippe ; Bonnefond, Amélie
Publisher:London: Nature Publishing Group UK
Journal title:International Journal of Obesity, 2020-02, Vol.44 (2), p.539-543
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Early prediction of the impact of public health policies on obesity and lifetime risk of type 2 diabetes: A modelling approach
Author / Creator:Bauvin, Pierre ; Delacôte, Claire ; Wandji, Line Carolle Ntandja ; Lassailly, Guillaume ; Raverdy, Violeta ; Pattou, François ; Deuffic-Burban, Sylvie ; Mathurin, Philippe
Publisher:United States: Public Library of Science
Journal title:PloS one, 2024-03, Vol.19 (3), p.e0301463-e0301463
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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
Author / Creator:Miguel-Escalada, Irene ; Bonàs-Guarch, Silvia ; Cebola, Inês ; Ponsa-Cobas, Joan ; Mendieta-Esteban, Julen ; Atla, Goutham ; Javierre, Biola M. ; Rolando, Delphine M. Y. ; Farabella, Irene ; Morgan, Claire C. ; García-Hurtado, Javier ; Beucher, Anthony ; Morán, Ignasi ; Pasquali, Lorenzo ; Ramos-Rodríguez, Mireia ; Appel, Emil V. R. ; Linneberg, Allan ; Gjesing, Anette P. ; Witte, Daniel R. ; Pedersen, Oluf ; Grarup, Niels ; Ravassard, Philippe ; Torrents, David ; Mercader, Josep M. ; Piemonti, Lorenzo ; Berney, Thierry ; de Koning, Eelco J. P. ; Kerr-Conte, Julie ; Pattou, François ; Fedko, Iryna O. ; Groop, Leif ; Prokopenko, Inga ; Hansen, Torben ; Marti-Renom, Marc A. ; Fraser, Peter ; Ferrer, Jorge
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2019-07, Vol.51 (7), p.1137-1148
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Neuromedin U uses Gαi2 and Gαo to suppress glucose-stimulated Ca2+ signaling and insulin secretion in pancreatic β cells
Author / Creator:Zhang, Weidong ; Sakoda, Hideyuki ; Nakazato, Yuki ; Islam, Md Nurul ; Pattou, François ; Kerr-Conte, Julie ; Nakazato, Masamitsu
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-04, Vol.16 (4), p.e0250232-e0250232
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Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery—a Post Hoc Analysis of the FibroTest Prospective Study
Author / Creator:Codjia, Tatiana ; Rebibo, Lionel ; François, Arnaud ; Lagnel, Carole ; Huet, Emmanuel ; Bekri, Soumeya ; Pattou, François ; Régimbeau, Jean-Marc ; Schwarz, Lilian
Publisher:New York: Springer US
Journal title:Obesity surgery, 2021-08, Vol.31 (8), p.3548-3556
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ArticlesPeer ReviewedFull Text
Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH
Author / Creator:L’homme, Laurent ; Sermikli, Benan Pelin ; Haas, Joel T. ; Fleury, Sébastien ; Quemener, Sandrine ; Guinot, Valentine ; Barreby, Emelie ; Esser, Nathalie ; Caiazzo, Robert ; Verkindt, Hélène ; Legendre, Benjamin ; Raverdy, Violeta ; Cheval, Lydie ; Paquot, Nicolas ; Piette, Jacques ; Legrand-Poels, Sylvie ; Aouadi, Myriam ; Pattou, François ; Staels, Bart ; Dombrowicz, David
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-08, Vol.15 (1), p.7173-18, Article 7173
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A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models
Author / Creator:Wirth, Fabian ; Heitz, Fabrice D. ; Seeger, Christine ; Combaluzier, Ioana ; Breu, Karin ; Denroche, Heather C. ; Thevenet, Julien ; Osto, Melania ; Arosio, Paolo ; Kerr-Conte, Julie ; Verchere, C. Bruce ; Pattou, François ; Lutz, Thomas A. ; Donath, Marc Y. ; Hock, Christoph ; Nitsch, Roger M. ; Grimm, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6294-6294, Article 6294
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ArticlesPeer ReviewedFull Text
A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice
Author / Creator:Demine, Stéphane ; Garcia Ribeiro, Rita ; Thevenet, Julien ; Marselli, Lorella ; Marchetti, Piero ; Pattou, François ; Kerr-Conte, Julie ; Devoogdt, Nick ; Eizirik, Decio L.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Diabetologia, 2020-04, Vol.63 (4), p.825-836
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Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes
Author / Creator:Maanaoui, Mehdi ; Debillon, Florence ; Lenain, Rémi ; Defrance, Frédérique ; Vantyghem, Marie-Christine ; Van Triempont, Marine ; Provôt, François ; Chetboun, Mikael ; Kerr-Conte, Julie ; Hamroun, Aghiles ; Frimat, Marie ; Raverdy, Violeta ; Pattou, François ; Hazzan, Marc ; Glowacki, François
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-12, Vol.14 (1), p.32081-10, Article 32081
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ArticlesPeer ReviewedFull Text
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells
Author / Creator:Trabelsi, Mohamed-Sami ; Daoudi, Mehdi ; Prawitt, Janne ; Ducastel, Sarah ; Touche, Véronique ; Sayin, Sama I. ; Perino, Alessia ; Brighton, Cheryl A. ; Sebti, Yasmine ; Kluza, Jérôme ; Briand, Olivier ; Dehondt, Hélène ; Vallez, Emmanuelle ; Dorchies, Emilie ; Baud, Grégory ; Spinelli, Valeria ; Hennuyer, Nathalie ; Caron, Sandrine ; Bantubungi, Kadiombo ; Caiazzo, Robert ; Reimann, Frank ; Marchetti, Philippe ; Lefebvre, Philippe ; Bäckhed, Fredrik ; Gribble, Fiona M. ; Schoonjans, Kristina ; Pattou, François ; Tailleux, Anne ; Staels, Bart ; Lestavel, Sophie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-07, Vol.6 (1), p.7629-7629, Article 7629
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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
Author / Creator:Pasquali, Lorenzo ; Gaulton, Kyle J ; Rodríguez-Seguí, Santiago A ; Mularoni, Loris ; Miguel-Escalada, Irene ; Akerman, İldem ; Tena, Juan J ; Morán, Ignasi ; Gómez-Marín, Carlos ; van de Bunt, Martijn ; Ponsa-Cobas, Joan ; Castro, Natalia ; Nammo, Takao ; Cebola, Inês ; García-Hurtado, Javier ; Maestro, Miguel Angel ; Pattou, François ; Piemonti, Lorenzo ; Berney, Thierry ; Gloyn, Anna L ; Ravassard, Philippe ; Skarmeta, José Luis Gómez ; Müller, Ferenc ; McCarthy, Mark I ; Ferrer, Jorge
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2014-02, Vol.46 (2), p.136-143
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ArticlesPeer ReviewedFull Text
Pancreatoduodenectomy for Neuroendocrine Tumors in Patients with Multiple Endocrine Neoplasia Type 1: An AFCE (Association Francophone de Chirurgie Endocrinienne) and GTE (Groupe d’étude des Tumeurs E...
Author / Creator:Santucci, Nicolas ; Gaujoux, Sébastien ; Binquet, Christine ; Reichling, Cynthia ; Lifante, Jean-Christophe ; Carnaille, Bruno ; Pattou, François ; Mirallié, Eric ; Facy, Olivier ; Mathonnet, Muriel ; Goudet, Pierre
Publisher:Cham: Springer International Publishing
Journal title:World journal of surgery, 2021-06, Vol.45 (6), p.1794-1802
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Performance of Biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in Patients with Severe Obesity: Meta Analysis of Individual Patient Data
Author / Creator:Poynard, Thierry ; Lassailly, Guillaume ; Diaz, Emmanuel ; Clement, Karine ; Caïazzo, Robert ; Tordjman, Joan ; Munteanu, Mona ; Perazzo, Hugo ; Demol, Bernard ; Callafe, Robert ; Pattou, François ; Charlotte, Frederic ; Bedossa, Pierre ; Mathurin, Philippe ; Ratziu, Vlad
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e30325
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The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series
Author / Creator:Maanaoui, Mehdi ; Chetboun, Mikael ; Top, Isabelle ; Elsermans, Vincent ; Kerr-Conte, Julie ; Le Mapihan, Kristell ; Defrance, Frederique ; Gmyr, Valéry ; Hubert, Thomas ; Labalette, Myriam ; Hazzan, Marc ; Vantyghem, Marie-Christine ; Pattou, François
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-07, Vol.12 (1), p.12463-12463, Article 12463
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Salvage Robotic Roux-en-Y Fistulojejunostomy for Chronic Gastro-Colic Fistula After Laparoscopic Sleeve Gastrectomy
Author / Creator:Mancini, Adrian ; Vangelder, Vincent ; Caiazzo, Robert ; Marciniak, Camille ; Daoud, Naïma Oukhouya ; Patel, Neil ; Pattou, François ; Baud, Grégory
Publisher:New York: Springer US
Journal title:Obesity surgery, 2021-04, Vol.31 (4), p.1899-1900
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Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
Author / Creator:Ichimura, Atsuhiko ; Hirasawa, Akira ; Poulain-Godefroy, Odile ; Bonnefond, Amélie ; Hara, Takafumi ; Yengo, Loïc ; Kimura, Ikuo ; Leloire, Audrey ; Liu, Ning ; Iida, Keiko ; Choquet, Hélène ; Besnard, Philippe ; Lecoeur, Cécile ; Vivequin, Sidonie ; Ayukawa, Kumiko ; Takeuchi, Masato ; Ozawa, Kentaro ; Tauber, Maithé ; Maffeis, Claudio ; Morandi, Anita ; Buzzetti, Raffaella ; Elliott, Paul ; Pouta, Anneli ; Jarvelin, Marjo-Riitta ; Körner, Antje ; Kiess, Wieland ; Pigeyre, Marie ; Caiazzo, Roberto ; Van Hul, Wim ; Van Gaal, Luc ; Horber, Fritz ; Balkau, Beverley ; Lévy-Marchal, Claire ; Rouskas, Konstantinos ; Kouvatsi, Anastasia ; Hebebrand, Johannes ; Hinney, Anke ; Scherag, Andre ; Pattou, François ; Meyre, David ; Koshimizu, Taka-aki ; Wolowczuk, Isabelle ; Tsujimoto, Gozoh ; Froguel, Philippe
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-03, Vol.483 (7389), p.350-354
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A Predictive Model of Weight Loss After Roux-en-Y Gastric Bypass up to 5 Years After Surgery: a Useful Tool to Select and Manage Candidates to Bariatric Surgery
Author / Creator:Seyssel, Kevin ; Suter, Michel ; Pattou, François ; Caiazzo, Robert ; Verkindt, Helene ; Raverdy, Violeta ; Jolivet, Mathieu ; Disse, Emmanuel ; Robert, Maud ; Giusti, Vittorio
Publisher:New York: Springer US
Journal title:Obesity surgery, 2018-11, Vol.28 (11), p.3393-3399
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Lysosomal degradation of newly formed insulin granules contributes to β cell failure in diabetes

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The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity

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Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL

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The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward

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Early prediction of the impact of public health policies on obesity and lifetime risk of type 2 diabetes: A modelling approach

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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

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Neuromedin U uses Gαi2 and Gαo to suppress glucose-stimulated Ca2+ signaling and insulin secretion in pancreatic β cells

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Evolution of Non-alcoholic Fatty Liver Disease (NAFLD) Biomarkers in Response to Weight Loss 1 Year After Bariatric Surgery—a Post Hoc Analysis of the FibroTest Prospective Study

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Adipose tissue macrophage infiltration and hepatocyte stress increase GDF-15 throughout development of obesity to MASH

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A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models

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A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice

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Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes

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Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

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Pancreatoduodenectomy for Neuroendocrine Tumors in Patients with Multiple Endocrine Neoplasia Type 1: An AFCE (Association Francophone de Chirurgie Endocrinienne) and GTE (Groupe d’étude des Tumeurs E...

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Performance of Biomarkers FibroTest, ActiTest, SteatoTest, and NashTest in Patients with Severe Obesity: Meta Analysis of Individual Patient Data

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The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series

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Salvage Robotic Roux-en-Y Fistulojejunostomy for Chronic Gastro-Colic Fistula After Laparoscopic Sleeve Gastrectomy

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Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human

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A Predictive Model of Weight Loss After Roux-en-Y Gastric Bypass up to 5 Years After Surgery: a Useful Tool to Select and Manage Candidates to Bariatric Surgery

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