Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersectin...
Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis
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Publisher
Cham: Springer International Publishing
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Language
English
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Publisher
Cham: Springer International Publishing
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Contents
In human metabolism, pyruvate dehydrogenase complex (PDC) is one of the most intricate and large multimeric protein systems representing a central hub for cellular homeostasis. The worldwide used antiepileptic drug valproic acid (VPA) may potentially induce teratogenicity or a mild to severe hepatic toxicity, where the underlying mechanisms are not...
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Full title
Dihydrolipoamide dehydrogenase, pyruvate oxidation, and acetylation-dependent mechanisms intersecting drug iatrogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072406
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072406
Other Identifiers
ISSN
1420-682X,1420-9071
E-ISSN
1420-9071
DOI
10.1007/s00018-021-03996-3
