PDGF receptor mutations in human diseases
PDGF receptor mutations in human diseases
About this item
Full title
Author / Creator
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
PDGFRA
and
PDGFRB
are classical proto-oncogenes that encode receptor tyrosine kinases responding to platelet-derived growth factor (PDGF).
PDGFRA
mutations are found in gastrointestinal stromal tumors (GISTs), inflammatory fibroid polyps and gliomas, and
PDGFRB
mutations drive myofibroma development. In addition, chromosomal re...
Alternative Titles
Full title
PDGF receptor mutations in human diseases
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072557
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072557
Other Identifiers
ISSN
1420-682X,1420-9071
E-ISSN
1420-9071
DOI
10.1007/s00018-020-03753-y
