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Abnormal X chromosome inactivation and tumor development

Abnormal X chromosome inactivation and tumor development

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11104905

Abnormal X chromosome inactivation and tumor development

About this item

Full title

Abnormal X chromosome inactivation and tumor development

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2020-08, Vol.77 (15), p.2949-2958

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

During embryonic development, one of the two X chromosomes of a mammalian female cell is randomly inactivated by the X chromosome inactivation mechanism, which is mainly dependent on the regulation of the non-coding RNA X-inactive specific transcript at the X chromosome inactivation center. There are three proteins that are essential for X-inactive...

Alternative Titles

Full title

Abnormal X chromosome inactivation and tumor development

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11104905

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11104905

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-020-03469-z

How to access this item