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Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate My...

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate My...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11133959

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control

About this item

Full title

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2023-05, Vol.24 (5), p.855-868

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Tuberculosis (TB), caused by
Mycobacterium tuberculosis
(
Mtb
), is a global cause of death. Granuloma-associated lymphoid tissue (GrALT) correlates with protection during TB, but the mechanisms of protection are not understood. During TB, the transcription factor IRF4 in T cells but not B cells is required for the generation of the T

Alternative Titles

Full title

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11133959

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11133959

Other Identifiers

ISSN

1529-2908,1529-2916

E-ISSN

1529-2916

DOI

10.1038/s41590-023-01476-3

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