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Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by...

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158900

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β‐catenin/TCF

About this item

Full title

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β‐catenin/TCF

Publisher

Melbourne, Australia: Blackwell Publishing Asia

Journal title

Cancer science, 2008-06, Vol.99 (6), p.1139-1146

Language

English

Formats

Publication information

Publisher

Melbourne, Australia: Blackwell Publishing Asia

More information

Scope and Contents

Contents

The Drosophila Notum gene, which is regulated by the Wingless pathway, encodes a secreted hydrolase that modifies heparan sulfate proteoglycans. In comparative analysis of the gene expression profiles in primary human hepatocellular carcinomas (HCC) and normal organs, we observed that the human ortholog of Drosophila Notum was overexpressed markedl...

Alternative Titles

Full title

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β‐catenin/TCF

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158900

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158900

Other Identifiers

ISSN

1347-9032,1349-7006

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2008.00814.x

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