Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant e...
Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Language
English
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Scope and Contents
Contents
Cetuximab (Erbitux, IMC‐C225) is a monoclonal antibody targeted to the epidermal growth factor receptor (EGFR). To clarify the mode of antitumor action of cetuximab, we examined antibody‐dependent cellular cytotoxicity (ADCC) activity against several tumor cell lines expressing wild‐type or mutant EGFR. ADCC activity and complement‐dependent cytoly...
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Full title
Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11159318
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11159318
Other Identifiers
ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2007.00510.x