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Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant e...

Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant e...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11159318

Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor

About this item

Full title

Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor

Publisher

Melbourne, Australia: Blackwell Publishing Asia

Journal title

Cancer science, 2007-08, Vol.98 (8), p.1275-1280

Language

English

Formats

Publication information

Publisher

Melbourne, Australia: Blackwell Publishing Asia

More information

Scope and Contents

Contents

Cetuximab (Erbitux, IMC‐C225) is a monoclonal antibody targeted to the epidermal growth factor receptor (EGFR). To clarify the mode of antitumor action of cetuximab, we examined antibody‐dependent cellular cytotoxicity (ADCC) activity against several tumor cell lines expressing wild‐type or mutant EGFR. ADCC activity and complement‐dependent cytoly...

Alternative Titles

Full title

Antibody‐dependent cellular cytotoxicity of cetuximab against tumor cells with wild‐type or mutant epidermal growth factor receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11159318

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11159318

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2007.00510.x

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