N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivit...
N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Language
English
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Contents
The glycosylation of cell surface proteins is important for cancer biology processes such as cellular proliferation or metastasis. α1,6‐Fucosyltransferase (FUT8) transfers a fucose residue to n‐linked oligosaccharides on glycoproteins. Herein, we study the effect of fucosylation on epidermal growth factor receptor (EGFR) activity and sensitivity to...
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Full title
N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160090
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160090
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ISSN
1347-9032,1349-7006
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2008.00847.x