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N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivit...

N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivit...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160090

N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

About this item

Full title

N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

Publisher

Melbourne, Australia: Blackwell Publishing Asia

Journal title

Cancer science, 2008-08, Vol.99 (8), p.1611-1617

Language

English

Formats

Publication information

Publisher

Melbourne, Australia: Blackwell Publishing Asia

More information

Scope and Contents

Contents

The glycosylation of cell surface proteins is important for cancer biology processes such as cellular proliferation or metastasis. α1,6‐Fucosyltransferase (FUT8) transfers a fucose residue to n‐linked oligosaccharides on glycoproteins. Herein, we study the effect of fucosylation on epidermal growth factor receptor (EGFR) activity and sensitivity to...

Alternative Titles

Full title

N‐Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160090

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160090

Other Identifiers

ISSN

1347-9032,1349-7006

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2008.00847.x

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