BTK drives neutrophil activation for sterilizing antifungal immunity
BTK drives neutrophil activation for sterilizing antifungal immunity
About this item
Full title
Author / Creator
Desai, Jigar V , Zarakas, Marissa A , Wishart, Andrew L , Roschewski, Mark , Aufiero, Mariano A , Donkò, Agnes , Wigerblad, Gustaf , Shlezinger, Neta , Plate, Markus , James, Matthew R , Lim, Jean K , Uzel, Gulbu , Bergerson, Jenna Re , Fuss, Ivan , Cramer, Robert A , Franco, Luis M , Clark, Emily S , Khan, Wasif N , Yamanaka, Daisuke , Chamilos, Georgios , El-Benna, Jamel , Kaplan, Mariana J , Staudt, Louis M , Leto, Thomas L , Holland, Steven M , Wilson, Wyndham H , Hohl, Tobias M and Lionakis, Michail S
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
We describe a previously unappreciated role for Bruton's tyrosine kinase (BTK) in fungal immune surveillance against aspergillosis, an unforeseen complication of BTK inhibitors (BTKi) used for treating B cell lymphoid malignancies. We studied BTK-dependent fungal responses in neutrophils from diverse populations, including healthy donors, patients...
Alternative Titles
Full title
BTK drives neutrophil activation for sterilizing antifungal immunity
Authors, Artists and Contributors
Author / Creator
Zarakas, Marissa A
Wishart, Andrew L
Roschewski, Mark
Aufiero, Mariano A
Donkò, Agnes
Wigerblad, Gustaf
Shlezinger, Neta
Plate, Markus
James, Matthew R
Lim, Jean K
Uzel, Gulbu
Bergerson, Jenna Re
Fuss, Ivan
Cramer, Robert A
Franco, Luis M
Clark, Emily S
Khan, Wasif N
Yamanaka, Daisuke
Chamilos, Georgios
El-Benna, Jamel
Kaplan, Mariana J
Staudt, Louis M
Leto, Thomas L
Holland, Steven M
Wilson, Wyndham H
Hohl, Tobias M
Lionakis, Michail S
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178547
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178547
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI176142
