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Evolutionarily divergent mTOR remodels translatome for tissue regeneration

Evolutionarily divergent mTOR remodels translatome for tissue regeneration

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11181899

Evolutionarily divergent mTOR remodels translatome for tissue regeneration

About this item

Full title

Evolutionarily divergent mTOR remodels translatome for tissue regeneration

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2023-08, Vol.620 (7972), p.163-171

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

An outstanding mystery in biology is why some species, such as the axolotl, can regenerate tissues whereas mammals cannot
1
. Here, we demonstrate that rapid activation of protein synthesis is a unique feature of the injury response critical for limb regeneration in the axolotl (
Ambystoma
mexicanum
). By applying polysome sequencing...

Alternative Titles

Full title

Evolutionarily divergent mTOR remodels translatome for tissue regeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11181899

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11181899

Other Identifiers

ISSN

0028-0836,1476-4687

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06365-1

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