Evolutionarily divergent mTOR remodels translatome for tissue regeneration
Evolutionarily divergent mTOR remodels translatome for tissue regeneration
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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An outstanding mystery in biology is why some species, such as the axolotl, can regenerate tissues whereas mammals cannot
1
. Here, we demonstrate that rapid activation of protein synthesis is a unique feature of the injury response critical for limb regeneration in the axolotl (
Ambystoma
mexicanum
). By applying polysome sequencing...
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Evolutionarily divergent mTOR remodels translatome for tissue regeneration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11181899
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11181899
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06365-1