C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation
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Publisher
England: Nature Publishing Group
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Language
English
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Publisher
England: Nature Publishing Group
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Contents
Clostridioides difficile infection (CDI) is a major cause of healthcare-associated gastrointestinal infections
. The exaggerated colonic inflammation caused by C. difficile toxins such as toxin B (TcdB) damages tissues and promotes C. difficile colonization
, but how TcdB causes inflammation is unclear. Here we report that TcdB induces neurog...
Alternative Titles
Full title
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11188852
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11188852
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ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06607-2
