Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in...
Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease
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United States: John Wiley and Sons Inc
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English
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United States: John Wiley and Sons Inc
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INTRODUCTION
Tau aggregation into neurofibrillary tangles in Alzheimer's disease (AD) is a dynamic process involving changes in tau phosphorylation, isoform composition, and morphology. To facilitate studies of tangle maturity, we developed an image analysis pipeline to study antibody labeling signatures that can distinguish tangle maturity leve...
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Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11247694
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11247694
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ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.13922