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Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in...

Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11247694

Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease

About this item

Full title

Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease

Publisher

United States: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-07, Vol.20 (7), p.4803-4817

Language

English

Formats

Publication information

Publisher

United States: John Wiley and Sons Inc

More information

Scope and Contents

Contents

INTRODUCTION
Tau aggregation into neurofibrillary tangles in Alzheimer's disease (AD) is a dynamic process involving changes in tau phosphorylation, isoform composition, and morphology. To facilitate studies of tangle maturity, we developed an image analysis pipeline to study antibody labeling signatures that can distinguish tangle maturity leve...

Alternative Titles

Full title

Characterization of neurofibrillary tangle immunophenotype signatures to classify tangle maturity in Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11247694

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11247694

Other Identifiers

ISSN

1552-5260,1552-5279

E-ISSN

1552-5279

DOI

10.1002/alz.13922

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