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Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity s...

Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11289786

Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing

About this item

Full title

Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2022-12, Vol.19 (12), p.1578-1589

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

We present proximity sequencing (Prox-seq) for simultaneous measurement of proteins, protein complexes and mRNAs in thousands of single cells. Prox-seq combines proximity ligation assay with single-cell sequencing to measure proteins and their complexes from all pairwise combinations of targeted proteins, providing quadratically scaled multiplexing...

Alternative Titles

Full title

Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11289786

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11289786

Other Identifiers

ISSN

1548-7091,1548-7105

E-ISSN

1548-7105

DOI

10.1038/s41592-022-01684-z

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