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Strategies for Improving CAR T Cell Persistence in Solid Tumors

Strategies for Improving CAR T Cell Persistence in Solid Tumors

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11352972

Strategies for Improving CAR T Cell Persistence in Solid Tumors

About this item

Full title

Strategies for Improving CAR T Cell Persistence in Solid Tumors

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2024-08, Vol.16 (16), p.2858

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

CAR T cells require optimization to be effective in patients with solid tumors. There are many barriers affecting their ability to succeed. One barrier is persistence, as to achieve an optimal antitumor response, infused CAR T cells must engraft and persist. This singular variable is impacted by a multitude of factors-the CAR T cell design, lymphod...

Alternative Titles

Full title

Strategies for Improving CAR T Cell Persistence in Solid Tumors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11352972

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11352972

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers16162858

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