Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
About this item
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Author / Creator
Chu, Yanshuo , Dai, Enyu , Li, Yating , Han, Guangchun , Pei, Guangsheng , Ingram, Davis R. , Thakkar, Krupa , Qin, Jiang-Jiang , Dang, Minghao , Le, Xiuning , Hu, Can , Deng, Qing , Sinjab, Ansam , Gupta, Pravesh , Wang, Ruiping , Hao, Dapeng , Peng, Fuduan , Yan, Xinmiao , Liu, Yunhe , Song, Shumei , Zhang, Shaojun , Heymach, John V. , Reuben, Alexandre , Elamin, Yasir Y. , Pizzi, Melissa P. , Lu, Yang , Lazcano, Rossana , Hu, Jian , Li, Mingyao , Curran, Michael , Futreal, Andrew , Maitra, Anirban , Jazaeri, Amir A. , Ajani, Jaffer A. , Swanton, Charles , Cheng, Xiang-Dong , Abbas, Hussein A. , Gillison, Maura , Bhat, Krishna , Lazar, Alexander J. , Green, Michael , Litchfield, Kevin , Kadara, Humam , Yee, Cassian and Wang, Linghua
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Tumor-infiltrating T cells offer a promising avenue for cancer treatment, yet their states remain to be fully characterized. Here we present a single-cell atlas of T cells from 308,048 transcriptomes across 16 cancer types, uncovering previously undescribed T cell states and heterogeneous subpopulations of follicular helper, regulatory and prolifer...
Alternative Titles
Full title
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Authors, Artists and Contributors
Author / Creator
Dai, Enyu
Li, Yating
Han, Guangchun
Pei, Guangsheng
Ingram, Davis R.
Thakkar, Krupa
Qin, Jiang-Jiang
Dang, Minghao
Le, Xiuning
Hu, Can
Deng, Qing
Sinjab, Ansam
Gupta, Pravesh
Wang, Ruiping
Hao, Dapeng
Peng, Fuduan
Yan, Xinmiao
Liu, Yunhe
Song, Shumei
Zhang, Shaojun
Heymach, John V.
Reuben, Alexandre
Elamin, Yasir Y.
Pizzi, Melissa P.
Lu, Yang
Lazcano, Rossana
Hu, Jian
Li, Mingyao
Curran, Michael
Futreal, Andrew
Maitra, Anirban
Jazaeri, Amir A.
Ajani, Jaffer A.
Swanton, Charles
Cheng, Xiang-Dong
Abbas, Hussein A.
Gillison, Maura
Bhat, Krishna
Lazar, Alexander J.
Green, Michael
Litchfield, Kevin
Kadara, Humam
Yee, Cassian
Wang, Linghua
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11421770
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11421770
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-023-02371-y
