Cholesterol-Dependent Serotonin Insertion Controlled by Gangliosides in Model Lipid Membranes
Cholesterol-Dependent Serotonin Insertion Controlled by Gangliosides in Model Lipid Membranes
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Publisher
Switzerland: MDPI AG
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Language
English
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Switzerland: MDPI AG
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Contents
Serotonin is distinct among synaptic neurotransmitters because it is amphipathic and released from synaptic vesicles at concentrations superior to its water solubility limit (270 mM in synaptic vesicles for a solubility limit of 110 mM). Hence, serotonin is mostly aggregated in the synaptic cleft, due to extensive aromatic stacking. This important...
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Full title
Cholesterol-Dependent Serotonin Insertion Controlled by Gangliosides in Model Lipid Membranes
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Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11432689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11432689
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms251810194
