Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in l...
Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli
About this item
Full title
Author / Creator
Lin, Xiuyu , Chen, Weicheng , Yang, Guilin , Zhang, Jiazhu , Wang, Huilin , Liu, Zeyu , Xi, Ying , Ren, Tao , Liu, Bo and Sui, Pengfei
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Severe viral pneumonia can induce rapid expansion of KRT5+ basal-like cells in small airways and alveoli; this forms a scar-like structure that persists in the injured alveoli and impedes normal alveolar epithelium regeneration. In this study, we investigated the mechanism by which viral infection induced this remodeling response. Through comparing...
Alternative Titles
Full title
Viral infection induces inflammatory signals that coordinate YAP regulation of dysplastic cells in lung alveoli
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11444164
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11444164
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI176828
