Delta‐6 desaturase FADS2 is a tumor‐promoting factor in cholangiocarcinoma
Delta‐6 desaturase FADS2 is a tumor‐promoting factor in cholangiocarcinoma
About this item
Full title
Author / Creator
Hasegawa, Kohsei , Fujimori, Haruna , Nakatani, Kohta , Takahashi, Masatomo , Izumi, Yoshihiro , Bamba, Takeshi , Nakamura‐Shima, Mao , Shibuya‐Takahashi, Rie , Mochizuki, Mai , Wakui, Yuta , Abue, Makoto , Iwai, Wataru , Fukushi, Daisuke , Satoh, Kennichi , Yamaguchi, Kazunori , Shindo, Norihisa , Yasuda, Jun , Asano, Naoki , Imai, Takayuki , Asada, Yukinori , Katori, Yukio and Tamai, Keiichi
Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
England: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Cholangiocarcinoma is a fatal disease with limited therapeutic options. We screened genes required for cholangiocarcinoma tumorigenicity and identified FADS2, a delta‐6 desaturase. FADS2 depletion reduced in vivo tumorigenicity and cell proliferation. In clinical samples, FADS2 was expressed in cancer cells but not in stromal cells. FADS2 inhibitio...
Alternative Titles
Full title
Delta‐6 desaturase FADS2 is a tumor‐promoting factor in cholangiocarcinoma
Authors, Artists and Contributors
Author / Creator
Fujimori, Haruna
Nakatani, Kohta
Takahashi, Masatomo
Izumi, Yoshihiro
Bamba, Takeshi
Nakamura‐Shima, Mao
Shibuya‐Takahashi, Rie
Mochizuki, Mai
Wakui, Yuta
Abue, Makoto
Iwai, Wataru
Fukushi, Daisuke
Satoh, Kennichi
Yamaguchi, Kazunori
Shindo, Norihisa
Yasuda, Jun
Asano, Naoki
Imai, Takayuki
Asada, Yukinori
Katori, Yukio
Tamai, Keiichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11447924
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11447924
Other Identifiers
ISSN
1347-9032,1349-7006
E-ISSN
1349-7006
DOI
10.1111/cas.16306
