Proteogenomic analysis integrated with electronic health records data reveals disease-associated var...
Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans
About this item
Full title
Author / Creator
Tahir, Usman A , Barber, Jacob L , Cruz, Daniel E , Kars, Meltem Ece , Deng, Shuliang , Tuftin, Bjoernar , Gillman, Madeline G , Benson, Mark D , Robbins, Jeremy M , Chen, Zsu-Zsu , Rao, Prashant , Katz, Daniel H , Farrell, Laurie , Sofer, Tamar , Hall, Michael E , Ekunwe, Lynette , Tracy, Russell P , Durda, Peter , Taylor, Kent D , Liu, Yongmei , Johnson, W Craig , Guo, Xiuqing , Chen, Yii-Der Ida , Manichaikul, Ani W , Jain, Deepti , Wang, Thomas J , Reiner, Alex P , Natarajan, Pradeep , Itan, Yuval , Rich, Stephen S , Rotter, Jerome I , Wilson, James G , Raffield, Laura M , Gerszten, Robert E and NHLBI Trans-Omics for Precision Medicine Consortium
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
BACKGROUNDMost GWAS of plasma proteomics have focused on White individuals of European ancestry, limiting biological insight from other ancestry-enriched protein quantitative loci (pQTL).METHODSWe conducted a discovery GWAS of approximately 3,000 plasma proteins measured by the antibody-based Olink platform in 1,054 Black adults from the Jackson He...
Alternative Titles
Full title
Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans
Authors, Artists and Contributors
Author / Creator
Barber, Jacob L
Cruz, Daniel E
Kars, Meltem Ece
Deng, Shuliang
Tuftin, Bjoernar
Gillman, Madeline G
Benson, Mark D
Robbins, Jeremy M
Chen, Zsu-Zsu
Rao, Prashant
Katz, Daniel H
Farrell, Laurie
Sofer, Tamar
Hall, Michael E
Ekunwe, Lynette
Tracy, Russell P
Durda, Peter
Taylor, Kent D
Liu, Yongmei
Johnson, W Craig
Guo, Xiuqing
Chen, Yii-Der Ida
Manichaikul, Ani W
Jain, Deepti
Wang, Thomas J
Reiner, Alex P
Natarajan, Pradeep
Itan, Yuval
Rich, Stephen S
Rotter, Jerome I
Wilson, James G
Raffield, Laura M
Gerszten, Robert E
NHLBI Trans-Omics for Precision Medicine Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11527441
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11527441
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI181802
