Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase act...
Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity
About this item
Full title
Author / Creator
Pallavicini, Gianmarco , Moccia, Amanda , Iegiani, Giorgia , Parolisi, Roberta , Peirent, Emily R , Berto, Gaia Elena , Lorenzati, Martina , Tshuva, Rami Y , Ferraro, Alessia , Balzac, Fiorella , Turco, Emilia , Salvi, Shachi U , Myklebust, Hedvig F , Wang, Sophia , Eisenberg, Julia , Chitale, Maushmi , Girgla, Navjit S , Boda, Enrica , Reiner, Orly , Buffo, Annalisa , Di Cunto, Ferdinando and Bielas, Stephanie L
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Brain size and cellular heterogeneity are tightly regulated by species-specific proliferation and differentiation of multipotent neural progenitor cells (NPCs). Errors in this process are among the mechanisms of primary hereditary microcephaly (MCPH), a group of disorders characterized by reduced brain size and intellectual disability. Biallelic ci...
Alternative Titles
Full title
Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity
Authors, Artists and Contributors
Author / Creator
Moccia, Amanda
Iegiani, Giorgia
Parolisi, Roberta
Peirent, Emily R
Berto, Gaia Elena
Lorenzati, Martina
Tshuva, Rami Y
Ferraro, Alessia
Balzac, Fiorella
Turco, Emilia
Salvi, Shachi U
Myklebust, Hedvig F
Wang, Sophia
Eisenberg, Julia
Chitale, Maushmi
Girgla, Navjit S
Boda, Enrica
Reiner, Orly
Buffo, Annalisa
Di Cunto, Ferdinando
Bielas, Stephanie L
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11527453
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11527453
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI175435
