Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Pre...
Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies
About this item
Full title
Author / Creator
Tariot, Pierre N. , Riviere, Marie‐Emmanuelle , Salloway, Stephen , Burns, Jeffrey M. , Snaedal, Jón G. , Borowsky, Beth , Lopez, Cristina Lopez , Liu, Fonda , Rouzade‐Dominguez, Marie‐Laure , Cazorla, Pilar , Mousseau, Marie‐Catherine , Arkuszewski, Michal , Ricart, Javier , Viglietta, Vissia , Sui, Yihan , Caputo, Angelika , Langbaum, Jessica B. , Reiman, Eric M. and Graf, Ana
Publisher
United States: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
INTRODUCTION
The Alzheimer's Prevention Initiative (API) Generation Studies evaluated the BACE inhibitor umibecestat for Alzheimer's disease (AD) prevention. The studies were terminated early, and the reversibility of umibecestat's side effects was assessed.
METHODS
Cognitively unimpaired 60‐ to 75‐year‐old apolipoprotein E (APOE) ε4 homoz...
Alternative Titles
Full title
Reversibility of cognitive worsening observed with BACE inhibitor umibecestat in the Alzheimer's Prevention Initiative (API) Generation Studies
Authors, Artists and Contributors
Author / Creator
Riviere, Marie‐Emmanuelle
Salloway, Stephen
Burns, Jeffrey M.
Snaedal, Jón G.
Borowsky, Beth
Lopez, Cristina Lopez
Liu, Fonda
Rouzade‐Dominguez, Marie‐Laure
Cazorla, Pilar
Mousseau, Marie‐Catherine
Arkuszewski, Michal
Ricart, Javier
Viglietta, Vissia
Sui, Yihan
Caputo, Angelika
Langbaum, Jessica B.
Reiman, Eric M.
Graf, Ana
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11567862
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11567862
Other Identifiers
ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.14237
