YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovaria...
YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer
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Publisher
England: Portland Press Ltd
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Language
English
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Publisher
England: Portland Press Ltd
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Contents
The high-grade serous ovarian cancer (HG-SOC) is a notoriously challenging disease, characterized by a rapid peritoneal dissemination. HG-SOC cells leverage actin-rich membrane protrusions, known as invadopodia, to degrade the surrounding extracellular matrix (ECM) and invade, initiating the metastatic cascade. In HG-SOC, the endothelin-1 (ET-1)/en...
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Full title
YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11609349
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11609349
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ISSN
0144-8463,1573-4935
E-ISSN
1573-4935
DOI
10.1042/BSR20241320