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YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovaria...

YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovaria...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11609349

YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer

About this item

Full title

YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer

Publisher

England: Portland Press Ltd

Journal title

Bioscience reports, 2024-12, Vol.44 (12)

Language

English

Formats

Publication information

Publisher

England: Portland Press Ltd

More information

Scope and Contents

Contents

The high-grade serous ovarian cancer (HG-SOC) is a notoriously challenging disease, characterized by a rapid peritoneal dissemination. HG-SOC cells leverage actin-rich membrane protrusions, known as invadopodia, to degrade the surrounding extracellular matrix (ECM) and invade, initiating the metastatic cascade. In HG-SOC, the endothelin-1 (ET-1)/en...

Alternative Titles

Full title

YAP signaling orchestrates the endothelin-1-guided invadopodia formation in high-grade serous ovarian cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11609349

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11609349

Other Identifiers

ISSN

0144-8463,1573-4935

E-ISSN

1573-4935

DOI

10.1042/BSR20241320

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