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Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL‐1 Ubiquitination

Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL‐1 Ubiquitination

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11705406

Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL‐1 Ubiquitination

About this item

Full title

Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL‐1 Ubiquitination

Publisher

England: John Wiley & Sons, Inc

Journal title

CNS neuroscience & therapeutics, 2025-01, Vol.31 (1), p.e70191-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

ABSTRACT
Objective
This study aims to investigate how the E3 ubiquitin ligase LITAF influences mitochondrial autophagy by modulating MCL‐1 ubiquitination, and its role in the development of epilepsy.
Methods
Employing single‐cell RNA sequencing (scRNA‐seq) to analyze brain tissue from epilepsy patients, along with high‐throughput transc...

Alternative Titles

Full title

Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL‐1 Ubiquitination

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11705406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11705406

Other Identifiers

ISSN

1755-5930,1755-5949

E-ISSN

1755-5949

DOI

10.1111/cns.70191

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