ROCK inhibitors alter brain proteomic profiles and tau phosphorylation in iPSC‐derived human neurons...
ROCK inhibitors alter brain proteomic profiles and tau phosphorylation in iPSC‐derived human neurons and mouse model of Alzheimer’s disease
About this item
Full title
Author / Creator
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
We aim to investigate efficacies of Ras homolog (Rho)‐associated kinases (ROCK) inhibitors on Alzheimer’s disease (AD) pathological proteins in human induced pluripotent stem cell (iPSC)‐differentiated human neurons and the P301S tau transgenic mouse model (PS19).
Method
Quantitative liquid chromatography‐mass spectrometry (LC‐M...
Alternative Titles
Full title
ROCK inhibitors alter brain proteomic profiles and tau phosphorylation in iPSC‐derived human neurons and mouse model of Alzheimer’s disease
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709550
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709550
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.091474
