Chimeric hippocampal organotypic slices enable the in vitro investigation of human iPSC‐derived micr...
Chimeric hippocampal organotypic slices enable the in vitro investigation of human iPSC‐derived microglia in a three‐dimensional environment with preserved neural network activity
About this item
Full title
Author / Creator
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
Formats
Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
More information
Scope and Contents
Contents
Background
Microglial cells have emerged as key players in the pathogenesis of Alzheimer’s disease (AD). They act as a first line defense and fulfil a crucial role during brain development and circuit homeostasis. Microglia are involved in the removal of debris, control neural activity, regulate synaptic plasticity, and synapse pruning. Normal m...
Alternative Titles
Full title
Chimeric hippocampal organotypic slices enable the in vitro investigation of human iPSC‐derived microglia in a three‐dimensional environment with preserved neural network activity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709818
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11709818
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.088649