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Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing ABCA7’s transcriptome insigh...

Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing ABCA7’s transcriptome insigh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710306

Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing ABCA7’s transcriptome insights in Alzheimer’s disease

About this item

Full title

Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing ABCA7’s transcriptome insights in Alzheimer’s disease

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2025-01, Vol.20 (Suppl 1), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

Subjects

More information

Scope and Contents

Contents

Background
ABCA7, an important risk gene for AD, encodes a transporter implicated in lipid transport and phagocytosis, and its disruptions have been linked to AD pathogenesis. However, the impact of these mutations on AD risk is complex due to their interaction with a multifaceted transcriptional architecture and cell type‐specificexpression pat...

Alternative Titles

Full title

Deciphering a Single‐cell atlas and loss‐of‐function analysis revealing ABCA7’s transcriptome insights in Alzheimer’s disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710306

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710306

Other Identifiers

ISSN

1552-5260

E-ISSN

1552-5279

DOI

10.1002/alz.092265

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