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Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710563

Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

About this item

Full title

Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

Subjects

More information

Scope and Contents

Contents

Background
Genome‐wide association studies suggest mutations in endolysosomal genes are linked to Alzheimer’s disease (AD). Defective lysosomal function has been corroborated as a feature of AD by neuropathological and cell biology studies. PLD3 is a homolog of the phospholipase D family localized to lysosomes. Genetic variants in PLD3 are assoc...

Alternative Titles

Full title

Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710563

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710563

Other Identifiers

ISSN

1552-5260

E-ISSN

1552-5279

DOI

10.1002/alz.087739

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