Commonalities in the lipid profile shift in ApoE ε4 risk variant and mild cognitive impairment highl...
Commonalities in the lipid profile shift in ApoE ε4 risk variant and mild cognitive impairment highlight acyl chain remodeling
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Hoboken: John Wiley and Sons Inc
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Language
English
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Hoboken: John Wiley and Sons Inc
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Background
At least one‐third of the identified risk alleles from Genome Wide Association Studies of Alzheimer’s disease (AD) are involved in lipid metabolism, lipid transport, or direct lipid binding. BIN1 which is also known as Amphiphysin 2; and PICALM which are involved in phosphoinositide metabolism and binding rank just below the highest r...
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Full title
Commonalities in the lipid profile shift in ApoE ε4 risk variant and mild cognitive impairment highlight acyl chain remodeling
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710570
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ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.087508