Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse mod...
Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse model of tauopathy
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Hoboken: John Wiley and Sons Inc
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Language
English
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Publisher
Hoboken: John Wiley and Sons Inc
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Background
Tau aggregation is the major cause of several neurodegenerative tauopathies. Tau interaction with other proteins affects the formation of tau aggregates with seeding activity but less is known about its effects on tau‐seed properties. Our previous study revealed that Bassoon (BSN), a presynaptic protein, interacts with tau‐seed, exace...
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Full title
Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse model of tauopathy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710633
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710633
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ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.090096