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Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse mod...

Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse mod...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710633

Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse model of tauopathy

About this item

Full title

Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse model of tauopathy

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

Subjects

More information

Scope and Contents

Contents

Background
Tau aggregation is the major cause of several neurodegenerative tauopathies. Tau interaction with other proteins affects the formation of tau aggregates with seeding activity but less is known about its effects on tau‐seed properties. Our previous study revealed that Bassoon (BSN), a presynaptic protein, interacts with tau‐seed, exace...

Alternative Titles

Full title

Protein degradation impairment and synapse elimination by microglia in BSN P3866A knock‐in mouse model of tauopathy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710633

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11710633

Other Identifiers

ISSN

1552-5260

E-ISSN

1552-5279

DOI

10.1002/alz.090096

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