Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing...
Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab
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Author / Creator
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
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Publication information
Publisher
Hoboken: John Wiley and Sons Inc
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Background
Clinical trials of anti‐Aβ monoclonal antibodies in Alzheimer disease (AD) typically infer target engagement from Aβ positron emission tomography (PET) and/or cerebrospinal fluid (CSF) Aβ42/40 biomarker outcomes that measure Aβ deposits indirectly and/or incompletely. Assessment of postmortem tissue is needed to directly investigate t...
Alternative Titles
Full title
Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713102
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.095436