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Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing...

Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713102

Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab

About this item

Full title

Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab

Publisher

Hoboken: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-12, Vol.20 (S8), p.n/a

Language

English

Formats

Publication information

Publisher

Hoboken: John Wiley and Sons Inc

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Background
Clinical trials of anti‐Aβ monoclonal antibodies in Alzheimer disease (AD) typically infer target engagement from Aβ positron emission tomography (PET) and/or cerebrospinal fluid (CSF) Aβ42/40 biomarker outcomes that measure Aβ deposits indirectly and/or incompletely. Assessment of postmortem tissue is needed to directly investigate t...

Alternative Titles

Full title

Anti‐amyloid‐β treatment effects on dominantly inherited Alzheimer disease neuropathology: comparing autopsy findings with biomarker outcomes from the DIAN‐TU‐001 trial of gantenerumab or solanezumab

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713102

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11713102

Other Identifiers

ISSN

1552-5260

E-ISSN

1552-5279

DOI

10.1002/alz.095436

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