Estimating age at Aβ onset in the 1946 British birth cohort: exploring the influence of APOE ɛ4 carr...
Estimating age at Aβ onset in the 1946 British birth cohort: exploring the influence of APOE ɛ4 carriership and sex
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Publisher
Hoboken: John Wiley and Sons Inc
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Language
English
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Publisher
Hoboken: John Wiley and Sons Inc
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Background
Cerebral Aβ accumulates decades before symptom onset in AD. Sampled iterative local approximation (SILA, Betthauser et al. 2022) is a technique for estimating time from Aβ positivity (Aβ+) using Aβ‐PET. Here we explore the influence of APOE‐ɛ4 carriership and sex on estimated age of Aβ+ (EAAβ) in primarily cognitively normal individua...
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Full title
Estimating age at Aβ onset in the 1946 British birth cohort: exploring the influence of APOE ɛ4 carriership and sex
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11714739
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11714739
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ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.092486