Estimating the time between Aβ positivity and elevated regional tau in preclinical AD
Estimating the time between Aβ positivity and elevated regional tau in preclinical AD
About this item
Full title
Author / Creator
the Insight 46 team , Coath, William , Betthauser, Tobey J. , Teague, Jordan P , Arstad, Erik , Awais, Ramla , Sander, Kerstin , Scott, Catherine J , Thomas, David L , Dickson, John , Markiewicz, Pawel J , Barkhof, Frederik , Schöll, Michael , Richards, Marcus , Fox, Nick C , Cash, David M and Schott, Jonathan M
Publisher
Hoboken: John Wiley and Sons Inc
Journal title
Language
English
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Publication information
Publisher
Hoboken: John Wiley and Sons Inc
Subjects
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Scope and Contents
Contents
Background
Understanding when Aβ positive cognitively normal individuals develop tau pathology has important implications for treatment with anti‐Aβ therapies. We employed a changepoint regression approach to estimate time from Aβ‐PET positivity to regionally elevated tau‐PET in a population‐based cohort of primarily cognitively unimpaired indiv...
Alternative Titles
Full title
Estimating the time between Aβ positivity and elevated regional tau in preclinical AD
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11715906
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11715906
Other Identifiers
ISSN
1552-5260
E-ISSN
1552-5279
DOI
10.1002/alz.092286
