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Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prost...

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prost...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735106

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice

About this item

Full title

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2025-01, Vol.135 (2), p.1-18

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Phenotypic plasticity is a hallmark of cancer and is increasingly realized as a mechanism of resistance to androgen receptor-targeted (AR-targeted) therapy. Now that many prostate cancer (PCa) patients are treated upfront with AR-targeted agents, it is critical to identify actionable mechanisms that drive phenotypic plasticity, to prevent the emerg...

Alternative Titles

Full title

Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735106

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11735106

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI175680

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