Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3
Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Aneuploidy typically poses challenges for cell survival and growth. However, recent studies have identified exceptions where aneuploidy is beneficial for cells with mutations in certain regulatory genes. Our research reveals that cells lacking the spindle checkpoint gene BUB3 exhibit aneuploidy of select chromosomes. While the spindle checkpoint is...
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Aneuploidy of specific chromosomes is beneficial to cells lacking spindle checkpoint protein Bub3
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11819610
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11819610
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1011576