TMEM16F regulates pathologic α‐synuclein secretion and spread in cellular and mouse models of Parkin...
TMEM16F regulates pathologic α‐synuclein secretion and spread in cellular and mouse models of Parkinson's disease
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Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
One of the main hallmarks of Parkinson's disease (PD) pathology is the spread of the aggregate‐prone protein α‐synuclein (α‐syn), which can be detected in the plasma and cerebrospinal fluid of patients as well as in the extracellular environment of neuronal cells. The secreted α‐syn can exhibit “prion‐like” behavior and transmission to naïve cells...
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Full title
TMEM16F regulates pathologic α‐synuclein secretion and spread in cellular and mouse models of Parkinson's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11822650
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11822650
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ISSN
1474-9718,1474-9726
E-ISSN
1474-9726
DOI
10.1111/acel.14387
