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Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic...

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11880380

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

About this item

Full title

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2025-03, Vol.16 (1), p.2174-20

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. Here we develop a mouse intracranial pre–olivary pretectal nucleus (OPN) optic tract injury model and demonstrate that Pten/Socs3 knockout and CNTF expression in retinal ganglion cells (RGCs) p...

Alternative Titles

Full title

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11880380

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11880380

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-025-57445-x

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