Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic...
Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. Here we develop a mouse intracranial pre–olivary pretectal nucleus (OPN) optic tract injury model and demonstrate that Pten/Socs3 knockout and CNTF expression in retinal ganglion cells (RGCs) p...
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Full title
Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11880380
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11880380
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57445-x
