Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Contents
The trimeric Cdk7–cyclin H–Mat1 complex comprises the kinase subunit of basal transcription factor TFIIH and has been shown to function as a cyclin‐dependent kinase (Cdk)‐activating kinase. Herein we report that disruption of the murine
Mat1
gene leads to peri‐implantation lethality coincident with depletion of maternal Mat1 protein. In cultu...
Alternative Titles
Full title
Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_125252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_125252
Other Identifiers
ISSN
0261-4189,1460-2075
E-ISSN
1460-2075
DOI
10.1093/emboj/20.11.2844
