Differences in Electrostatic Properties at Antibody–Antigen Binding Sites: Implications for Specific...
Differences in Electrostatic Properties at Antibody–Antigen Binding Sites: Implications for Specificity and Cross-Reactivity
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Publisher
United States: Elsevier Inc
Journal title
Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Antibodies HyHEL8, HyHEL10, and HyHEL26 (HH8, HH10, and HH26, respectively) recognize highly overlapping epitopes on hen egg-white lysozyme (HEL) with similar affinities, but with different specificities. HH8 binding to HEL is least sensitive toward mutations in the epitope and thus is most cross-reactive, HH26 is most sensitive, whereas the sensit...
Alternative Titles
Full title
Differences in Electrostatic Properties at Antibody–Antigen Binding Sites: Implications for Specificity and Cross-Reactivity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1302377
Other Identifiers
ISSN
0006-3495
E-ISSN
1542-0086
DOI
10.1016/S0006-3495(02)75302-2
